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Leaded Gas Was a Known Poison the Day It Was Invented (2016)

Original article
smithsonianmag.com|20 points|8 comments|by downbad_|Jul 11, 2026

The Toxic Legacy: Leaded Gas Was a Known Poison from Day One

For a significant portion of the twentieth century, the use of leaded gasoline was viewed as standard practice completely normal. However, the reality was far more sinister: lead is a potent neurotoxin, and its combustion resulted in catastrophic environmental and human health consequences.

The Quest to Stop the "Knock"

The story begins in 1921. Thomas Midgley Jr., an engineer at General Motors, informed his supervisor, Charles Kettering, that he had identified an additive capable of eliminating "knocking" in internal combustion engines.

What was "knocking"? It was a loud, disruptive noise that rendered vehicles less efficient and intimidated potential buyers. Kettering, who had previously invented the self-starter, was desperate for a solution.

Midgley experimented with a vast array of substances to find an "antiknock" agent, including:

  • Aluminum chloride
  • Ethyl acetate
  • Camphor
  • Melted butter

The Choice: Profit vs. Safety

While Midgley found that ethanol was the most effective option, General Motors rejected it. The reasoning was purely financial and strategic:

FeatureEthanolTetraethyl Lead (TEL)
EffectivenessHighHigh
Patentable?NoYes
Corporate ControlLowHigh
Industry ViewHated by Du PontEmbraced by Oil Companies

Midgley instead pivoted to tetraethyl lead (also known as lead tetraethyl), a compound discovered way back in 1854. Chemically, it can be represented as: (CH3)4Pb\text{(CH}_3\text{)}_4\text{Pb}(CH3​)4​Pb

A Known Danger

Despite its utility in raising the fuel's "octane" (combustibility), TEL was notoriously dangerous. A Du Pont executive described it in 1922 as:

"a colorless liquid of sweetish odor, very poisonous if absorbed through the skin, resulting in lead poisoning almost immediately."

Despite this knowledge, the product hit the market in February 1923. Ironically, Midgley was absent from the launch because he was confined to his bed, suffering from severe lead poisoning.

Regulatory Blindness

The rollout was not without controversy. After five deaths occurred at a New Jersey Standard Oil refinery in 1924, public concern grew. However, a 1926 Public Health Service report concluded that there was "no reason to prohibit the sale of leaded gasoline," provided the factory workers were protected.

While researchers found lead in the blood of all tested drivers and residues in garage corners, they dismissed it, claiming low levels were tolerable. Regarding the risk of cumulative exposure over time, the report essentially stated: "But, of course, that would be another generation’s problem."

The Long-Term Fallout

The EPA eventually engaged in a protracted legal battle with fuel producers to phase out leaded gas starting in the mid-1970s, but the damage was already done. The atmospheric lead continues to haunt the environment.

The most tragic victims were children, whose developing systems are highly susceptible to neurological injury. Research (cited by Kevin Drum and James Lincoln Kitman) links childhood lead exposure to:

  • Lowered IQ
  • Hyperactivity
  • Learning disabilities
  • Behavioral problems
  • Increased rates of violent crime

Standard Stations filling station in California, circa 1939

The contamination persists in the soil and air of many regions today, proving that the "problem for another generation" has finally arrived.


Related Reading:

  • A Short Picture History of Gas Stations
  • Henry Bliss: America's First Pedestrian Fatality
  • The Man Who Invented Two of the Deadliest Substances of the 20th Century